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1

Distribution of tetrodotoxin in the body of the blue-ringed octopus (Hapalochlaena maculosa)

Mari Yotsu-Yamashita, Dietrich Mebs, Wolfgang Flachsenberger

Journal:

Year:

2007

Language:

english

File:

PDF, 236 KB

english, 2007

2

Synthesis of Skeletal Analogues of Saxitoxin Derivatives and Evaluation of Their Inhibitory Activity on Sodium Ion Channels NaV1.4 and NaV1.5

Ryoko Shinohara, Takafumi Akimoto, Dr. Osamu Iwamoto, Dr. Takatsugu Hirokawa, Prof. Dr. Mari Yotsu-Yamashita, Prof. Dr. Kaoru Yamaoka, Prof. Dr. Kazuo Nagasawa

Journal:

Chemistry - A European Journal

Year:

2011

Language:

english

File:

PDF, 598 KB

english, 2011

3

CHEMISTRY OF PUFFER FISH TOXIN

Yotsu-Yamashita, Mari

Journal:

Year:

2001

Language:

english

File:

PDF, 205 KB

english, 2001

4

Total Synthesis and Biological Evaluation of (+)-Gambieric Acid A and Its Analogues

Ishigai, Kazuya, Fuwa, Haruhiko, Hashizume, Keisuke, Fukazawa, Ryo, Cho, Yuko, Yotsu-Yamashita, Mari, Sasaki, Makoto

Journal:

Chemistry - A European Journal

Year:

2013

Language:

english

File:

PDF, 707 KB

english, 2013

5

Tetrodotoxin and Its Analogues in the Pufferfish Arothron hispidus and A. nigropunctatus from the Solomon Islands: A Comparison of Their Toxin Profiles with the Same Species from Okinawa, Japan

Puilingi, Clyde, Kudo, Yuta, Cho, Yuko, Konoki, Keiichi, Yotsu-Yamashita, Mari

Journal:

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

6

Total Synthesis and Biological Evaluation of (+)-Neopeltolide and Its Analogues

Haruhiko Fuwa, Asami Saito, Shinya Naito, Keiichi Konoki, Mari Yotsu-Yamashita, Makoto Sasaki

Journal:

Chemistry - A European Journal

Year:

2009

Language:

english

File:

PDF, 452 KB

english, 2009

7

ChemInform Abstract: Chemistry of Puffer Fish Toxin

Mari Yotsu-Yamashita

Journal:

Year:

2001

File:

PDF, 24 KB

2001

8

Electrospray Ionization Mass Spectrometry of Tetrodotoxin and Its Analogs: Liquid Chromatography/Mass Spectrometry, Tandem Mass Spectrometry, and Liquid Chromatography/Tandem Mass Spectrometry

Yuki Shoji, Mari Yotsu-Yamashita, Teruo Miyazawa, Takeshi Yasumoto

Journal:

Analytical Biochemistry

Year:

2001

Language:

english

File:

PDF, 132 KB

english, 2001

9

Four new analogs of polycavernoside A

Mari Yotsu-Yamashita, Tetsuya Seki, Valerie J. Paul, Hideo Naoki, Takeshi Yasumoto

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 193 KB

english, 1995

10

5,6,11-trideoxytetrodotoxin from the puffer fish, fugu poecilonotus

Mari Yotsu-Yamashita, Yuki Yamagishi, Takeshi Yasumoto

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 242 KB

english, 1995

11

Hydrophilic interaction liquid chromatography–electrospray ionization mass spectrometry of tetrodotoxin and its analogs

Toshio Nakagawa, Junho Jang, Mari Yotsu-Yamashita

Journal:

Analytical Biochemistry

Year:

2006

Language:

english

File:

PDF, 325 KB

english, 2006

12

Binding of diarrheic shellfish poisoning toxins to okadaic acid binding proteins purified from the sponge Halichondria okadai

Keiichi Konoki, Kaori Saito, Hiroki Matsuura, Naoyuki Sugiyama, Yuko Cho, Mari Yotsu-Yamashita, Kazuo Tachibana

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 322 KB

english, 2010

13

Polycavernoside C and C2, the new analogs of the human lethal toxin polycavernoside A, from the red alga, Gracilaria edulis

Mari Yotsu-Yamashita, Kazumi Abe, Tetsuya Seki, Kenshu Fujiwara, Takeshi Yasumoto

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 190 KB

english, 2007

14

Synthesis and biological evaluation of analogs of the marine toxin polycavernoside A

Louis Barriault, Serge L. Boulet, Kenshu Fujiwara, Akio Murai, Leo A. Paquette, Mari Yotsu-Yamashita

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 194 KB

english, 1999

15

Purification, characterization, and cDNA cloning of a novel soluble saxitoxin and tetrodotoxin binding protein from plasma of the puffer fish, Fugu pardalis

Mari Yotsu-Yamashita, Atsuko Sugimoto, Takahiro Terakawa, Yuki Shoji, Teruo Miyazawa, Takeshi Yasumoto

Journal:

Year:

2001

Language:

english

File:

PDF, 1.51 MB

english, 2001

16

Optimization of simultaneous analysis of tetrodotoxin, 4-epitetrodotoxin, 4,9-anhydrotetrodotoxin, and 5,6,11-trideoxytetrodotoxin by hydrophilic interaction liquid chromatography–tandem mass spectrometry

Mari Yotsu-Yamashita, Jun-Ho Jang, Yuko Cho, Keiichi Konoki

Journal:

Forensic Toxicology

Year:

2011

Language:

english

File:

PDF, 258 KB

english, 2011

17

Ozonation of PC in ethanol: Separation and identification of a novel ethoxyhydroperoxide

Misako Tagiri-Endo, Kaori Ono, Kiyotaka Nakagawa, Mari Yotsu-Yamashita, Teruo Miyazawa

Journal:

Year:

2002

Language:

english

File:

PDF, 413 KB

english, 2002

18

Toxicity of Dangerous Prey: Variation of Tetrodotoxin Levels Within and Among Populations of the NewtTaricha granulosa

Charles T. Hanifin, Mari Yotsu-Yamashita, Takeshi Yasumoto, Edmund D. Brodie, Edmund D. Brodie

Journal:

Journal of Chemical Ecology

Year:

1999

Language:

english

File:

PDF, 1.01 MB

english, 1999

19

Variability of tetrodotoxin and of its analogues in the red-spotted newt, Notophthalmus viridescens (Amphibia: Urodela: Salamandridae)

Mari Yotsu-Yamashita, John Gilhen, Ronald W. Russell, Kenneth L. Krysko, Christian Melaun, Alexander Kurz, Silke Kauferstein, Dusan Kordis, Dietrich Mebs

Journal:

Year:

2012

Language:

english

File:

PDF, 547 KB

english, 2012

20

Tetrodotoxin does not protect red-spotted newts, Notophthalmus viridescens, from intestinal parasites

Dietrich Mebs, Mari Yotsu-Yamashita, Hanns Martin Seitz, Osamu Arakawa

Journal:

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

21

50. Tetrodotoxin in North-American Newts

Dietrich Mebs, Mari Yotsu-Yamashita

Journal:

Year:

2012

Language:

english

File:

PDF, 47 KB

english, 2012

22

Binding Properties of 3H-PbTx-3 and 3H-Saxitoxin to Brain Membranes and to Skeletal Muscle Membranes of Puffer Fish Fugu pardalis and the Primary Structure of a Voltage-Gated Na+ Channel α-Subunit (fMNa1) from Skeletal Muscle of F. pardalis

Mari Yotsu-Yamashita, Katsuhiko Nishimori, Yoko Nitanai, Masako Isemura, Atsuko Sugimoto, Takeshi Yasumoto

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 156 KB

english, 2000

23

Tetrodotoxin and its analogues in extracts from the toad Atelopus oxyrhynchus (family: Bufonidae)

Mari Yotsu-Yamashita, Dietrich Mebs, Takeshi Yasumoto

Journal:

Year:

1992

Language:

english

File:

PDF, 169 KB

english, 1992

24

Further report of the occurrence of tetrodotoxin in Atelopus species (family: Bufonidae)

Dietrich Mebs, Mari Yotsu-Yamashita, Takeshi Yasumoto, Stefan Lötters, Andreas Schlüter

Journal:

Year:

1995

Language:

english

File:

PDF, 215 KB

english, 1995

25

First occurrence of tetrodotoxin in a dendrobatid frog (Colostethus inguinalis), with further reports for the bufonid genus Atelopus

John W. Daly, Fabian Gusovsky, Charles W. Myers, Mari Yotsu-Yamashita, Takeshi Yasumoto

Journal:

Year:

1994

Language:

english

File:

PDF, 443 KB

english, 1994

26

Biological activity of 8,11-dideoxytetrodotoxin: lethality to mice and the inhibitory activity to cytotoxicity of ouabain and veratridine in mouse neuroblastoma cells, Neuro-2a

Mari Yotsu-Yamashita, Daisuke Urabe, Masanori Asai, Toshio Nishikawa, Minoru Isobe

Journal:

Year:

2003

Language:

english

File:

PDF, 88 KB

english, 2003

27

Distribution of tetrodotoxin, saxitoxin, and their analogs among tissues of the puffer fish Fugu pardalis

Junho Jang, Mari Yotsu-Yamashita

Journal:

Year:

2006

Language:

english

File:

PDF, 246 KB

english, 2006

28

Tetrodotoxin and its analogue 6-epitetrodotoxin in newts (Triturus spp.; Urodela, Salamandridae) from southern Germany

Mari Yotsu-Yamashita, Dietrich Mebs, Axel Kwet, Michael Schneider

Journal:

Year:

2007

Language:

english

File:

PDF, 101 KB

english, 2007

29

6,11-Dideoxytetrodotoxin from the puffer fish, Fugu pardalis

Jun-Ho Jang, Mari Yotsu-Yamashita

Journal:

Year:

2007

Language:

english

File:

PDF, 147 KB

english, 2007

30

Two critical residues in p-loop regions of puffer fish Na+ channels on TTX sensitivity

Satoshi Maruta, Kaoru Yamaoka, Mari Yotsu-Yamashita

Journal:

Year:

2008

Language:

english

File:

PDF, 270 KB

english, 2008

31

Accumulation of tetrodotoxin and 4,9-anhydrotetrodotoxin in cultured juvenile kusafugu Fugu niphobles by dietary administration of natural toxic komonfugu Fugu poecilonotus liver

Michiko Kono, Takashi Matsui, Kiyoshi Furukawa, Mari Yotsu-Yamashita, Kunio Yamamori

Journal:

Year:

2008

Language:

english

File:

PDF, 260 KB

english, 2008

32

Examination of transformation among tetrodotoxin and its analogs in the living cultured juvenile puffer fish, kusafugu, Fugu niphobles by intramuscular administration

Michiko Kono, Takashi Matsui, Kiyoshi Furukawa, Takuhiko Takase, Kunio Yamamori, Hideko Kaneda, Daisuke Aoki, Jun-Ho Jang, Mari Yotsu-Yamashita

Journal:

Year:

2008

Language:

english

File:

PDF, 445 KB

english, 2008

33

First report on toxins in the Panamanian toads Atelopus limosus, A. glyphus and A. certus

Mari Yotsu-Yamashita, Eiko Tateki

Journal:

Year:

2010

Language:

english

File:

PDF, 327 KB

english, 2010

34

Distribution of homologous proteins to puffer fish saxitoxin and tetrodotoxin binding protein in the plasma of puffer fish and among the tissues of Fugu pardalis examined by Western blot analysis

Mari Yotsu-Yamashita, Hiroe Yamaki, Natsumi Okoshi, Nao Araki

Journal:

Year:

2010

Language:

english

File:

PDF, 282 KB

english, 2010

35

The levels of tetrodotoxin and its analogue 6-epitetrodotoxin in the red-spotted newt, Notophthalmus viridescens

Mari Yotsu-Yamashita, Dietrich Mebs

Journal:

Year:

2001

Language:

english

File:

PDF, 147 KB

english, 2001

36

Occurrence of 11-oxotetrodotoxin in the red-spotted newt, Notophthalmus viridescens, and further studies on the levels of tetrodotoxin and its analogues in the newt's efts

Mari Yotsu-Yamashita, Dietrich Mebs

Journal:

Year:

2003

Language:

english

File:

PDF, 111 KB

english, 2003

37

Tissue distribution of tetrodotoxin in the red-spotted newt Notophthalmus viridescens

Dietrich Mebs, Osamu Arakawa, Mari Yotsu-Yamashita

Journal:

Year:

2010

Language:

english

File:

PDF, 1.03 MB

english, 2010

38

Interactions of the C-11 Hydroxyl of Tetrodotoxin with the Sodium Channel Outer Vestibule

Choudhary, Gaurav, Yotsu-Yamashita, Mari, Shang, Lisa, Yasumoto, Takeshi, Dudley, Samuel C.

Journal:

Biophysical Journal

Year:

2003

Language:

english

File:

PDF, 301 KB

english, 2003

39

Chemical and Etiological Studies on Tetrodotoxin and Its Analogs

Yasumoto, Takeshi, Yotsu-Yamashita, Mari

Journal:

Year:

1996

Language:

english

File:

PDF, 396 KB

english, 1996

40

Polycavernoside A: a novel glycosidic macrolide from the red alga Polycavernosa tsudai (Gracilaria edulis)

Yotsu-Yamashita, Mari, Haddock, Robert L., Yasumoto, Takeshi

Journal:

Journal of the American Chemical Society

Year:

1993

Language:

english

File:

PDF, 316 KB

english, 1993

41

Concise Synthesis and Biological Assessment of (+)-Neopeltolide and a 16-Member Stereoisomer Library of 8,9-Dehydroneopeltolide: Identification of Pharmacophoric Elements

Fuwa, Haruhiko, Kawakami, Masato, Noto, Kenkichi, Muto, Takashi, Suga, Yuto, Konoki, Keiichi, Yotsu-Yamashita, Mari, Sasaki, Makoto

Journal:

Chemistry - A European Journal

Year:

2013

Language:

english

File:

PDF, 714 KB

english, 2013

42

New Method for the Quantitative Determination of Major Protein Carbonyls, α-Aminoadipic and γ-Glutamic Semialdehydes: Investigation of the Formation Mechanism and Chemical Nature in Vitro and in Vivo

Akagawa, Mitsugu, Sasaki, Daisuke, Ishii, Yoshihisa, Kurota, Yayoi, Yotsu-Yamashita, Mari, Uchida, Koji, Suyama, Kyozo

Journal:

Chemical Research in Toxicology

Year:

2006

Language:

english

File:

PDF, 209 KB

english, 2006

43

Isolation of 6-Deoxytetrodotoxin from the Pufferfish, Takifugu pardalis , and a Comparison of the Effects of the C-6 and C-11 Hydroxy Groups of Tetrodotoxin on Its Activity

Kudo, Yuta, Finn, Julian, Fukushima, Kohei, Sakugawa, Satsuki, Cho, Yuko, Konoki, Keiichi, Yotsu-Yamashita, Mari

Journal:

Journal of Natural Products

Year:

2014

Language:

english

File:

PDF, 762 KB

english, 2014

44

Localization of pufferfish saxitoxin and tetrodotoxin binding protein (PSTBP) in the tissues of the pufferfish, Takifugu pardalis, analyzed by immunohistochemical staining

Yotsu-Yamashita, Mari, Okoshi, Natsumi, Watanabe, Kouichi, Araki, Nao, Yamaki, Hiroe, Shoji, Yuki, Terakawa, Takahiro

Journal:

Year:

2013

Language:

english

File:

PDF, 965 KB

english, 2013

45

Effect of 5-fluoro-2′-deoxyuridine on toxin production and cell cycle regulation in marine dinoflagellate, Alexandrium tamarense

Cho, Yuko, Ogawa, Motoo, Yotsu-Yamashita, Mari, Oshima, Yasukatsu

Journal:

Year:

2014

Language:

english

File:

PDF, 794 KB

english, 2014

46

The binding of okadaic acid analogs to recombinant OABP2.1 originally isolated from the marine sponge Halichondria okadai

Konoki, Keiichi, Onoda, Tatsuya, Furumochi, Sachie, Cho, Yuko, Yotsu-Yamashita, Mari, Yasumoto, Takeshi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 481 KB

english, 2013

47

Single-cell analysis of paralytic shellfish toxins in Alexandrium tamarense by HPLC with post-column fluorescent derivatization

Cho, Yuko, Ozeki, Ryoko, Yotsu-Yamashita, Mari, Oshima, Yasukatsu

Journal:

Year:

2013

Language:

english

File:

PDF, 796 KB

english, 2013

48

Synthesis of 5- and 8-Deoxytetrodotoxin

Satake, Yoshiki, Adachi, Masaatsu, Tokoro, Shouta, Yotsu-Yamashita, Mari, Isobe, Minoru, Nishikawa, Toshio

Journal:

Chemistry – An Asian Journal

Year:

2014

Language:

english

File:

PDF, 514 KB

english, 2014

49

Synthesis and identification of proposed biosynthetic intermediates of saxitoxin in the cyanobacterium Anabaena circinalis (TA04) and the dinoflagellate Alexandrium tamarense (Axat-2)

Tsuchiya, Shigeki, Cho, Yuko, Konoki, Keiichi, Nagasawa, Kazuo, Oshima, Yasukatsu, Yotsu-Yamashita, Mari

Journal:

Organic & Biomolecular Chemistry

Year:

2014

Language:

english

File:

PDF, 620 KB

english, 2014

50

Identification of Polycavernoside A as the Causative Agent of the Fatal Food Poisoning Resulting from Ingestion of the Red Alga Gracilaria edulis in the Philippines

Yotsu-Yamashita, Mari, Yasumoto, Takeshi, Yamada, Shunichi, Bajarias, Fe Farida A., Formeloza, Mirriam A., Romero, Marc Lawrence, Fukuyo, Yasuo

Journal:

Chemical Research in Toxicology

Year:

2004

Language:

english

File:

PDF, 221 KB

english, 2004